MOLECULAR IMMUNOLOGY RESEARCH GROUP

Andreas L Lopata Ph.D.

Comparative Genomics Centre,
Molecular Sciences Bldg 21, James Cook University,
Townsville, 4811, Queensland, Australia
Telephone: 61-7-4781 5463 Fax:  61-7-4781 6078
Email: Andreas.Lopata@jcu.edu.au



Qualifications
  • PhD (Medical Science), University of Cape Town (South Africa), 1999
  • MSc (Zoology), University of Düsseldorf (Germany), 1991
  • Bachelor of Science (Honours, Chemistry), University of Siegen (Germany) 1986

Specialty expertise areas

•    Seafood Allergen identification and molecular characterization
•    Development of allergen diagnostics
•    Marine Biotoxins analysis
•    Marine Parasites
•    Biomarkers in Aquaculture Research

Research areas

•    Molecular and immunological characterisation of allergenic proteins
•    Development of murine models of allergic diseases
•    Allergens and the immune system
•    Food safety
•    Detection and quantification of food and environmental allergens
•    Development of immunotherapeutics for food allergy




Qualifications

Specialty expertise areas

•    Seafood Allergen identification and molecular characterization
•    Development of allergen diagnostics
•    Marine Biotoxins analysis
•    Marine Parasites
•    Biomarkers in Aquaculture Research

Research areas

•    Molecular and immunological characterisation of allergenic proteins
•    Development of murine models of allergic diseases
•    Allergens and the immune system
•    Food safety
•    Detection and quantification of food and environmental allergens
•    Development of immunotherapeutics for food allergy

Credentials granted by professional / industry bodies

•    Associate Professor, School of Applied Sciences, RMIT University
•    Associate Professor, School of Public Health, University of Cape Town (UCT)
•    Adjunct Member, Institute of Infectious Diseases and Molecular Medicine (IIDMM), University of Cape Town (UCT)


Research activities

Almost half of the world’s population have allergies to one or more common environmental and/or food allergens. The allergic reaction is triggered by the activation of IgE(antibody)-binding cells, via specific receptore, in the exposed tissues leading to a series of cellular and immunological responses that are characteristic of an allergy reaction. The investigation of allergens and immunologic responses has moved to a more molecular approach to develop advanced strategies of detecting and treating allergy. The characterisation and generation of recombinant allergens are fundamental for the development of novel and improved diagnostics and future immunotherapeutics. The expertise in molecular and immuno-biochemical techniques has been applied in a range of international industry focuses and multidisciplinary seafood research areas. Current research projects involve national and international collaborators including South Africa, Germany, Norway, Japan and Canada.


Research accomplishments

Based on my extensive publication track record I have attracted various competitive international research grants bridging the research areas of molecular biology, immunology, health and aquaculture research. I have been Principal Investigator of over 30 competitive research projects supported by funding bodies such as GlaxoSmithKline, National Research Foundation, Medical Research Council, NIH (USA), FRDC, Asthma Foundation Victoria and the ABRS (Australian Biological Resource System). I have authored over 90 scientific articles, 19 reports and book chapters and 60 conference papers. During my 17 years of work in the field of allergy research I have successfully supervised 5 PhD students, 14 Masters and 10 Honours students and currently supervise 10 research students.


Research publications


LINKS:



Immunology, immune, immunogenetics, disease, risk, vaccine, Medical Genomics Research Group, Autoimmunity Research Group, Comparative Genomics Centre,  Key words: Autoimmune diabetes, gene, genome, allele, locus, inherited, disease, Type 1 diabetes mellitus, childhood diabetes, lupus, systemic lupus erythematosus, hemolytic anaemia, hemolytic anemia, Coombs' test, antinuclear antibodies, renal failure, glomerulonephritis, gastritis, type A gastritis, pernicious anemia, immunology, popular science, biology.