ANNUAL REPORT 2009 - 2010

Comparative Genomics Centre,
Molecular Sciences Bldg 21, James Cook University,
Townsville, 4811, Queensland, Australia
Telephone: 61-7-4781 6265 Fax:  61-7-4781 6078

    The Comparative Genomics Centre (CGC) is a research centre at James Cook University that studies the molecular basis of health and disease in a wide range of organisms, including staghorn coral, fruit fly and mice. The Centre is a focus of resources and expertise in genetics for the University and the region, with member laboratories covering a broad range of applications of genetics and genomics, including diagnostics, recombinant crops, the science of coral reef management and gene/environment interactions in autoimmune diseases.  Its member laboratories span three Schools in two Faculties.

The CGC now has an annual research income in excess of $8.5 M from peer-reviewed grants and research contracts and is funded by the National Health and Medical Research Council (NHMRC), the Australian Research Council, The Great Barrier Reef Marine Park Authority, The Marine and Tropical Sciences Research Facility, Dutch Science Foundation, MBD Energy, GHD, National and International Research Alliances Program, Ian Potter Foundation, Pro Bio Technology, National Climate Change Adaptation Research Facility, Fisheries Research & Development Corporation, Australian Centre for International Agricultural Research, MS Society, ARC Centre of Excellence for Coral Reef Studies, Lions Club and JCU intramural funding schemes.

The Centre’s 13 laboratories accommodate 17 honours students, 68 postgraduate students, 18 postdoctoral fellows and 15 research assistants. Over the last fifteen months, the CGC has had 101 scientific manuscripts published in internationally recognised scientific journals.

In mid-November 2009, Professor Ross Crozier last week died unexpectedly at work. Ross was one Australia's leading researchers in molecular ecology, molecular phylogeny and population genetic models, a Fellow of the American Association for the Advancement of Science, a Fellow of the Australian Academy of Science and a Foundation Member of the Comparative Genomics Centre. Throughout the short history of the CGC, Ross was a wonderful supporter, a much-valued advisor and an effective statesman. The work of the Crozier lab is being managed by Associate Professor Simon Robson and Ross’ senior postdoctoral fellow Dr Helge Schluns. Sadly, at the end of 2010, Helge will be leaving and the Sociogenomics laboratory will close.

The member laboratories of the CGC are:
1) The Medical Genomics Group (Group Head: Prof Alan Baxter)
The Medical Genomics Group is working to determine the genetic causes of autoimmune diseases using both cellular and genetic techniques. Current projects study: the genetics of autoimmune diabetes, multiple sclerosis gastritis and lupus in mice; the effects of mycobacteria on autoimmune diseases; and the role of immunoregulatory NKT cells in childhood diabetes. The lab is funded by the NHMRC, MSRA and the Lions Club.

2) The Coral Genomics Group (Group Head: Prof David Miller)
The Coral Genomics Group is studying a local Acropora (staghorn coral) as a model system, in order to investigate issues central to the evolution of animal genomes and developmental mechanisms. The laboratory is a member of the world leading ARC Centre of Excellence for Coral Reef Studies. 

3) The Biotechnology Group (Group Head: Prof James Burnell)
Biotechnology Group clones and expresses biological products of potential utility and is developing genetic recombinant plant crops with improved disease resistance and greater yields.

4) The Supramolecular Biology Group (Group Head: Dr Patrick Schaeffer)
The Supramolecular Biology Group (SSBG) focus is to study protein-ligand interactions and in particular Protein-DNA interactions. The discovery and characterization of novel protein interactions can lead to the production of new molecular tools with applications in the field of bio- and nanotechnology (e.g. molecular diagnostics, drug discovery, functional genomics and proteomics). The SSBG is currently developing innovative methods for the discovery, characterization and quantification of such interactions as well as novel ultrasensitive diagnostics. The research undertaken in the SSBG is multidisciplinary and spans across the disciplines of Biology, Biochemistry and Chemistry.

5) The Cellular Immunology Group (Group Head Ass/Prof Heinrich Korner)
The Cellular Immunology Group studies infections and inflammatory diseases in mice bearing targeted deletions of key immunological genes, in order to dissect the critical pathways involved in the initiation and resolution of immune responses.

6) The Psychogenetics Group (Group Head: Prof Bernard Baune)
The Psychogenetics Group studies the genetic control of inflammatory processes involved in the aetiology of neuropsychiatric problems, such as depression and cognitive decline. Current projects study: the effects of TNF on cognitive function; the role of TNF in neurodevelopment of the central nervous system; development of TNF targeted treatment strategies in the CNS.

7) The Drosophila Genetics Group (Group Head: Ass/Prof Bill Warren)
The Drosophila Genetics Group's main focus is to investigate human disease using the model organism Drosophila melanogaster (fruit fly). As Drosophila share many key genes regulating cell division in man, they can provide important insights into disorders of chromosome segregation and cell cycle regulation.

8) The Aquaculture Genetics Group (Group Head: Dr Dean Jerry)
The research focus of the Aquaculture Genetics Group at James Cook University is to acquire the statistical information and develop molecular tools that will allow the design and conduct of highly efficient selection programs for aquaculture species, primarily those farmed in tropical waters. Research conducted by the group falls within four major research strands – quantitative genetics, population genetics and development of molecular tools, gene expression analyses and chromosome manipulation. Aquaculture species currently worked with include the pearl oysters Pinctada maxima, P. margaritifera, P. fucata, barramundi Lates calcarifer, and redclaw Cherax quadricarinatus.

9) The Symbiosis Genomics Group (Group Head: Dr Bill Leggat) 
Symbiosis Genomics group focuses on linking changes in the gene expression of the dinoflagellate Symbiodinium to physiological of the algae and the intact coral holobiont (its host), and subsequent ecological changes. Research of this type can broadly be called ecological genomics. In particular this group is interested in how these dinoflagellates respond to human induced stress, such as climate change, what effects these changes have on the coral host and how these responses of the alga effect the future of coral reefs as we know them. This laboratory is a member of the world leading ARC Centre of Excellence for Coral Reef Studies

10) Parasite and Pest Genetics (Group Head: Prof David Blair)
Study organisms are parasitic flatworms, mainly the trematodes that infect humans, such as the Asian blood fluke and the lung flukes. Most of the field-work on parasites and some lab work is done in countries such as China, Japan, Sri Lanka, Vietnam and India.  We are also getting more involved with work on blood flukes of marine turtles.  These are a major, and apparently increasing, cause of morbidity and mortality.   In conjunction with the Algal Biology Group (see below), we are undertaking molecular identification of endemic and invasive microalgae in waters of the Great Barrier Reef.

11) The Conservation and Ecological Genetics Group (Group Head: Dr Michelle Waycott)
This group has a focus on problem solving research utilising a broad range of molecular genetic approaches on a diverse group of organisms. Research include numerous collaborative projects with other CGC groups, other JCU researchers and external researchers. Studies include population genetic, phylogenetic, molecular ecological and plant breeding approaches and we incorporate molecular and whole organism approaches into our studies. Current and recent research includes studies on seagrasses, mangrove, dugong, turtle, flying foxes, sea snakes, tassel ferns, mistletoes, Melaleuca, sandalwood and invasive species such as Green Mussel. Recent research directions involve the assessment of thresholds of vulnerability to changing climates and species adaptability, DNA barcoding to assess species diversity, evolutionary diversification rates and marker assisted screening of population genetic health. Established the Global Initiative to Barcode Seagrasses (GIBS) as a pilot for adopting DNA barcoding to assist in ecological and evolutionary studies of taxonomically difficult groups.

12) Algal Biology Group (Group Head: Dr Kirsten Heimann)
The Algal Biology Group runs the North Queensland Algal Identification / Culturing Facility, which isolates and establishes microalgal cultures from the GBR to screen for: biotechnological applications (such as biofuel potential, antiviral etc. effects), industrial purposes (such as potential animal feeds and aquaculture), morphological and genetic identification of invasives and novel organisms and potential for genetic enhancement of desirable traits for industrial / biotechnological applications.

Recent key publications include:

The Medical Genomics Group

Baune BT, Dannlowski U, Janssen DAG, Jordan MA, Ohrmann P, Bauer J, Domschke K, Arolt V, Kugel H, Baxter AG, Suslow T. (2010) The interleukin 1 beta (IL1B) gene is associated with failure to achieve remission and impaired emotion processing in major depression. Biol Psychiatry. 67(6):543-9. [0 (IF = 8.926)]

Godfrey DI, Stankovic S, Baxter AG. (2010) Raising the NKT family. Nature Immunology 11: 197-206. [15 (IF = 26)]

Godfrey DI, Stankovic S, Baxter AG. (2009) Developing NKT cells need their calcium. Nature Immunology 10: 231-233. [2 (IF = 26)]

Fletcher MT, Baxter AG. (2009) Clinical Application of NKT Cell Biology in Type 1 (Autoimmune) Diabetes Mellitus. Immunol Cell Biol 87: 315-23. [3 (IF = 4.2)]

Jordan MA, Poulton LD, Fletcher JM  and  Baxter AG. (2009) Allelic variation of Ets1 does not contribute to NK and NKT cell deficiencies in type 1 diabetes susceptible NOD mice. Rev Diabetic Stud 6: 104-116. [journal not indexed]

The Coral Genomics Group

Kitahara, Marcelo V., Cairns, Stephen D., and Miller, David J. (2010) Monophyletic origin of Caryophyllia (Scleractinia, Caryophylliidae), with descriptions of six new species. Systematics and Biodiversity, 8 (1). pp. 91-118. ISSN 1478-0933

Miller, David J., and Technau, Ulrich (2010) Understanding the evolution of multicellularity; insights from basal metazoans. BioEssays, 32 (2). pp. 175-178. ISSN 1521-1878

Seneca, Francois O., Forêt , Sylvain, Ball, Eldon E., Smith-Keune, Carolyn, Miller, David J., and van Oppen, Madeleine J.H. (2010) Patterns of gene expression in a scleractinian coral undergoing natural bleaching. Marine Biotechnology, 12 (5). pp. 594-604. ISSN 1436-2236

Reyes-Bermudez, A., and Miller, D.J. (2009) In vitro culture of cells derived from larvae of the staghorn coral Acropora millepora. Coral Reefs, 28 (4). pp. 859-864. ISSN 1432-0975

Zhou, et. al. (2009) The Schistosoma japonicum genome reveals features of host–parasite interplay. Nature, 460 . pp. 345-352. ISSN 1476-4687

Bay, Line K., Ulstrup, Karin E., Nielsen, H. Bjorn, Jarmer, Hanne, Goffard, Nicolas, Willis, Bette L., Miller, David J., and van Oppen, Madeleine J.H. (2009) Microarray analysis reveals transcriptional plasticity in the reef building coral Acropora millepora. Molecular Ecology, 18 (14). pp. 3062-3075. ISSN 1365-294X

Reyes-Bermudez, Alejandro, Lin, Zhiyi, Hayward, David C., Miller, David J., and Ball, Eldon E. (2009) Differential expression of three galaxin-related genes during settlement and metamorphosis in the scleractinian coral Acropora millepora. BMC Evolutionary Biology, 9 (178). - . ISSN 1471-2148

Iguchi, Akira, Morita, Masaya, Nakajima, Yuichi, Nishikawa, Akira, and Miller, David (2009) In vitro fertilization efficiency in Acropora digitifera. Zygote, 17 . pp. 225-227. ISSN 1469-8730

The Biotechnology Group

Burnell, Jim N. (2010) Cloning and characterization of Escherichia coli DUF299: a bifunctional ADP-dependent kinase - Pi-dependent pyrophosphorylase from bacteria. BMC Biochemistry, 11 (1). pp. 1-8. ISSN 1471-2091

Brinkman, Diane L., and Burnell, James N. (2009) Biochemical and molecular characterisation of cubozoan protein toxins. Toxicon, 54 (8). pp. 1162-1173. ISSN 1879-3150

Robillot, Cedric, Kineavy, Daniel, Burnell, James, and Llewellyn, Lyndon E. (2009) Synthesis of bifunctional saxitoxin analogues by biotinylation. Toxicon, 53 (4). pp. 460-465. ISSN 1879-3150

Krautwald, Martina, Maxwell, Philippa, Stuchbury, Grant, Holtum, Joe, Burnell, James, and Munch, Gerald (2009) The thiamine analogue and advanced glycation endproducts crosslink breaker ALT-711 does not interfere with transketolase activity. Open Longevity Science, 3 . pp. 11-15. ISSN 1876-326X

The Supramolecular Biology Group

Morin, Isabelle, Dixon, Nicholas E., and Schaeffer, Patrick M. (2010) Ultrasensitive detection of antibodies using a new Tus-Ter-lock immunoPCR system. Molecular BioSystems, 6 (7). pp. 1173-1175. ISSN 1742-2051

Dahdah, Dahdah B., Morin, Isabelle, Moreau, Morgane J.J., Dixon, Nicholas E., and Schaeffer, Patrick M. (2009) Site-specific covalent attachment of DNA to proteins using a photoactivatable Tus–Ter complex. Chemical Communications, 21 . pp. 3050-3052. ISSN 1364-548X

Schaeffer, Patrick, and Dixon, Nicholas (2009) Synthesis and applications of covalent protein-DNA conjugates. Australian Journal of Chemistry, 62 (10). pp. 1328-1332. ISSN 1445-0038

The Cellular Immunology Group

McAfoose, J., Korner, H., and Baune, B.T. (2009) The effects of TNF deficiency on age-related cognitive performance. Psychoneuroendocrinology, 34 (4). pp. 615-619. ISSN 1873-3360

Liston, Adrian, Kohler, Rachel, Townley, Scott, Haylock-Jacobs, Sarah, Comerford, Ian, Caon, Adriana, Webster, Julie, Harrison, Jodie, Swann, Jeremy, Clark-Lewis, Ian, Korner, Heinrich, and McColl, Shaun R. (2009) Inhibition of CCR6 function reduces the severity of experimental autoimmune encephalomyelitis via effects on the priming phase of the immune response. Journal of Immunology, 182 (5). pp. 3121-3130. ISSN 1550-6606

Wiede, Florian, Roomberg, Alicia, Cretney, Erika, Lechner, Anja, Fromm, Phillip, Wren, Leia, Smyth, Mark J., and Körner, Heinrich (2009) Age-dependent, polyclonal hyperactivation of T cells is reduced in TNF-negative gld/gld mice. Journal of Leukocyte Biology, 85 (1). pp. 108-116. ISSN 0741-5400

The Psychogenetics Group

Baune, Bernhard T., Dannlowski, Udo, Domschke, Katharina, Janssen, Debbie G.A., Jordan, Margaret A., Ohmann, Patricia, Bauer, Jochen, Biros, Erik, Arolt, Volker, Kugel, Harald, Baxter, Alan G., and Suslow, Thomas (2010) The interleukin 1 beta (IL1B) gene is associated with failure to achieve remission and impaired emotion processing in major depression. Biological Psychiatry, 67 (6). pp. 543-549. ISSN 1873-2402

Beste, C., Baune, B.T., Domschke, K., Falkenstein, M, and Konrad, C (2010) Paradoxical association of the brain-derived-neurotrophic-factor val66met genotype with response inhibition. Neuroscience, 166 (1). pp. 178-184. ISSN 1873-7544
Todder, D., and Baune, B.T. (2010) Quality of sleep in escitalopram-treated female patients with panic disorder. Human Psychopharmacology: clinicial & experimental, 25 (2). pp. 167-173. ISSN 0885-6222

Todder, D., and Baune, B.T. (2010) Quality of sleep in escitalopram-treated female patients with panic disorder. Human Psychopharmacology: clinicial & experimental, 25 (2). pp. 167-173. ISSN 0885-6222

Domschke, Katharina, Lawford, Bruce, Laje, Gonzalo, Berger, Klaus, Young, Ross, Morris, Phillip, Deckert, Jürgen, Arolt, Volker, McMahon, Francis J., and Baune, Bernhard T. (2010) Brain-derived neurotrophic factor (BDNF) gene: no major impact on antidepressant treatment response. International Journal of Neuropsychopharmacology , 13 (1). pp. 93-101. ISSN 1469-5111

Baune, B.T., Neuhauser, H., Ellert, U., and Berger, K. (2010) The role of the inflammatory markers ferritin, transferrin and fibrinogen in the relationship between major depression and cardiovascular disorders – the German Health Interview and Examination Survey. Acta Psychiatrica Scandinavica, 121 (2). pp. 135-142. ISSN 1600-0447

Lucae, Susanne, Ising, Marcus, Horstmann, Sonja, Baune, Bernhard T., Arolt, Volker, Muller-Myhsok, Bertram, Holsboer, Florian, and Domschke, Katharina (2010) HTR2A gene variation is involved in antidepressant treatment response. European Neuropsychopharmacology, 20 (1). pp. 65-68. ISSN 1873-7862

Dickinson, C., Quirk, F., Baune, B., Leicht, A., and Golledge, J. (2010) Quality of life in patients with peripheral arterial disease. Journal of Science and Medicine in Sport, 12 (S2). pp. 127-128. ISSN 1878-1861

Baune, Bernhard T., and Eyre, Harris (2010) Anti-inflammatory effects of antidepressant and atypical antipsychotic medication for the treatment of major depression and comorbid arthritis: a case report. Journal of Medical Case Reports, 4 (6). pp. 1-4. ISSN 1752-1947

Domschke, Katharina, Zavorotnyy, Maxim, Diemer, Julia, Nitsche, Sarina, Hohoff, Christa, Baune, Bernhard T., Deckert, Jurgen, Arolt, Volker, and Zwanzger, Peter (2010) COMT val158met influence on electroconvulsive therapy response in major depression. American Journal of Medical Genetics: Part B, 153B (1). pp. 286-290. ISSN 1552-485X

Caniato, Riccardo N., Stitch, Heribert L., Alvarenga , Marlies, Kraemer, Alexander, and Baune, Bernhard T. (2010) Erratum to: Changing rates of physical and psychosocial impairments over 9 years in cohorts of school beginners in Germany. Journal of Public Health, 18 (1). p. 93. ISSN 1741-3842

Bauer, M., Kasper, S., Dell'Osso, L., Pichot, W., Baune, B.T., Köhler, J., Jørgensen, L., Dencker-Vansvik, E., and Montgomery, S. (2010) Predictive factors of remission for treatment-resistant major depressive disorder (MDD) during treatment with extended-release quetiapine fumarate(quetiapine XR). International Journal of Psychiatry in Clinical Practice, 14 (S1). pp. 20-21. ISSN 1471-1788

Trollor, Julian N., Smith, Evelyn, Baune, Bernhard T., Kochan, Nicole A., Campbell, Lesley, Samaras, Katherine, Crawford, John, Brodaty, Henry, and Sachdev, Perminder (2010) Systemic inflammation is associated with MCI and its subtypes: The Sydney Memory and Aging Study. Dementia and Geriatric Cognitive Disorders, 30 (6). pp. 569-578. ISSN 1421-9824

Baune, Bernhard T., Schmidt, Wolf P., Roesler, Andreas, and Berger, Klaus (2009) Functional consequences of subcortical white matter lesions and MRI-defined brain infarct in an elderly general population. Journal of Geriatric Psychiatry and Neurology, 22 (4). pp. 266-273. ISSN 1552-5708

Caniato, Riccardo N., Gundabawady, Anand, Baune, Bernhard T., and Alvarenga, Marlies E. (2009) Malingered psychotic symptoms and quetiapine abuse in a forensic setting. Journal of Forensic Psychiatry and Psychology, 20 (6). pp. 928-935. ISSN 1478-9957

Kersting, Anette, Kroker, Kristin, Horstmann, Julia, Ohrmann, Patricia, Baune, Bernhard T., Arolt, Volker, and Suslow, Thomas (2009) Complicated grief in patients with unipolar depression. Journal of Affective Disorders, 118 (1). pp. 201-204. ISSN 1573-2517

Todder, Doron, Caliskan, Serdal, and Baune, Bernhard T. (2009) Longitudinal changes of day-time and night-time gross motor activity in clinical responders and non-responders of major depression. World Journal of Biological Psychiatry, 10 (4). pp. 276-284. ISSN 1814-1412

Schoing, Sonja, Zwitserlood, Pienie, Engelien, Almut, Behnken, Andreas, Kugel, Harald, Schiffbauer, Hagen, Lipina, Katharina, Pachur, Christine, Kersting, Anette, Dannlowski, Udo, Baune, Bernhard T., Zwanzger, Peter, Reker, Thomas, Heindel, Walter, Arolt, Volker, and Konrad, Carsten (2009) Working-memory fMRI reveals cingulate hyperactivation in euthymic major depression. Human Brain Mapping, 30 (9). pp. 2746-2756. ISSN 1097-0193

Pohle, K., Domschke, K., Roehrs, T., Arolt, V., and Baune, B.T. (2009) Medical comorbidity affects antidepressant treatment response in patients with melancholic depression. Psychotherapy and Psychosomatics, 78 (6). pp. 359-363. ISSN 1423-0348

Ising, Marcus, Lucae, Susanne, Binder, Elisabeth B., Bettecken, Thomas, Uhr, Manfred, Ripke, Stephan, Kohli, Martin A., Hennings, Johannes M., Horstmann, Sonja, Kloiber, Stefan, Menke, Andreas, Bondy, Brigitta, Rupprecht, Rainer, Domschke, Katharina, Baune, Bernhard T., Arolt, Volker, Rush, John, Holsboer, Florian, and Müller -Myhsok, Bertram (2009) A genomewide association study points to multiple loci that predict antidepressant drug treatment outcome in depression. Archives of General Psychiatry, 66 (9). pp. 966-975. ISSN 1538-3636

Todder, Doron, Fox, Michael, and Baune, Bernhard T. (2009) Body temperature in patients with panic disorder treated with escitalopram. Clinical Autonomic Research, 19 (4). pp. 255-258. ISSN 1619-1560

Millard, Fiona, and Baune, Bernhard (2009) Dementia – who cares?: a comparison of community needs and primary care services. Australian Family Physician, 38 (8). pp. 642-649. ISSN 0300-8495

Pedersen, Anya, Kuppers, Kerstin, Behnken, Andreas, Kroker, Kristin, Schoning, Sonja, Baune, Bernhard T., Rist, Fred, Arolt, Volker, and Suslow, Thomas (2009) Implicit and explicit procedural learning in patients recently remitted from severe major depression. Psychiatry Research, 169 (1). pp. 1-6. ISSN 1872-7123

Mond, Jonathan M., and Baune, Bernhard T. (2009) Overweight, medical comorbidity and health-related quality of life in a community sample of women and men. Obesity, 17 (8). pp. 1627-1634. ISSN 1930-739X

Pham, Tuan D., Eisenblättera, Uwe, Baune, Bernhard T., and Berger, Klaus (2009) Preprocessing film-copied MRI for studying morphological brain changes. Journal of Neuroscience Methods, 180 (2). pp. 352-362. ISSN 0165-0270

McAfoose, J., Korner, H., and Baune, B.T. (2009) The effects of TNF deficiency on age-related cognitive performance. Psychoneuroendocrinology, 34 (4). pp. 615-619. ISSN 1873-3360

Caniato, Riccardo N., Stitch, Heribert L., Alvarenga, Marlies, Kraemer, Alexander, and Baune, Bernhard T. (2009) Changing rates of physical and psychosocial impairments over 9 years in cohorts of school beginners in Germany. Journal of Public Health, 17 (2). pp. 137-144. ISSN 1741-3842

Sullivan, P.F., de Geus, E.J., Willemsen, G., James, M.R., Smit, J.H., Zandbelt, T., Arolt, V., Baune, B.T., Blackwood, D., Cichon, S., Coventry, W.L., Domschke, K., Farmer, A., Fava, M., Gordon, S.D., He, Q., Heath, A.C., Heutink, P., Holsboer, F., Hoogendijk, W.J., Hottenga, J.J., Hu, Y., Kohli, M., Lin, D., Lucae, S., MacIntyre, D.J., Maier, W., McGhee, K.A., McGuffin, P., Montgomery, G.W., Muir, W.J., Nolen, W.A., Nothen, M.M., Perlis, R.H., Pirlo, K., Posthuma, D., Rietschel, M., Rizzu, P., Schosser, A., Smit, A.B., Smoller, J.W., Tzeng, J-Y., van Dyck, R., Verhage, M., Zitman, F.G., Martin, N.G., Wray, N.R., Boomsma, D.I., and Penninx, B.W.J.H. (2009) Genome-wide association for major depressive disorder: a possible role for the presynaptic protein piccolo. Molecular Psychiatry, 14 (4). pp. 359-375. ISSN 1476-5578

Baune, Bernhard T., Caniato, Riccardo N., Arolt, Volker, and Berger, Klaus (2009) The effects of dysthymic disorder on health-related quality of life and disability days in persons with comorbid medical conditions in the general population. Psychotherapy and Psychosomatics, 78 (3). pp. 161-166. ISSN 1423-0348

Baune, Bernhard T. (2009) The puzzle of predicting the impact of brain infarcts on cognitive impairment in the aging brain. Stroke, 40 (3). pp. 667-669. ISSN 1524-4628

McAfoose, J., and Baune, B.T. (2009) Evidence for a cytokine model of cognitive function. Neuroscience & Biobehavioral Reviews, 33 (3). pp. 355-366. ISSN 0149-7634

McAfoose, J., and Baune, B. T. (2009) Exploring visual–spatial working memory: a critical review of concepts and models. Neuropsychology Review, 19 (1). pp. 130-142. ISSN 1573-6660

Alvarenga, Marlies E., Caniato, Riccardo N., Mauritz, Anika, Braun, Anja, Aljeesh, Yousef, and Baune, Bernhard (2009) Health service utilization in patients with major depression and co-morbid pain. Psychiatry and Clinical Neurosciences, 63 (1). pp. 101-106. ISSN 1323-1316

Dannlowski, Udo, Ohrmann, Patricia, Konrad, Carsten, Domschke, Katharina, Bauer, Jochen, Kugel, Harald, Hohoff, Christa, Schöning, Sonja, Kersting, Anette, Baune, Bernhard T., Mortensen, Lena S., Arolt, Volker, Zwitserlood, Pienie, Deckert, Jürgen, Heindel, Walter, and Suslow, Thomas (2009) Reduced amygdala–prefrontal coupling in major depression: association with MAOA genotype and illness severity. International Journal of Neuropsychopharmacology, 12 (1). pp. 11-22. ISSN 1469-5111

Baune, Bernard T., Roesler, Andreas, Knecht, Stefan, and Berger, Klaus (2009) Single and combined effects of cerebral white matter lesions and lacunar infarctions on cognitive function in an elderly population. Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 64A (1). pp. 118-124. ISSN 1758-535X

Boon, Helen Joanna, Tobias, Stephen, Baune, Bernhard, and Kennedy, Lee (2009) Ars Cooperativa Naturae. Ethical contingencies across medicine and education: a case study. International Journal of Interdisciplinary Social Sciences, 4 (6). pp. 41-67. ISSN 1833-1882

Baune, Bernhard T., Ponath, Gerald, Rothermundt, Matthias, Roesler, Andreas, and Berger, Klaus (2009) Association Between Cytokines and Cerebral MRI Changes in the Aging Brain. Journal of Geriatric Psychiatry and Neurology, 22 (1). pp. 23-34. ISSN 1552-5708

Baune, Bernhard (2009) Conceptual challenges of a tentative model of stress-induced depression. PLoS ONE, 4 (1). pp. 1-2. ISSN 1932-6203

Baune, Bernhard T., McAfoose, Jordan, Leach, Geraldine, Quirk, Francis, and Mitchell, David (2009) Impact of psychiatric and medical comorbidity on cognitive function in depression. Psychiatry and Clinical Neurosciences, 63 (3). pp. 392-400. ISSN 1323-1316

The Drosophila Genetics Group

Rutkowski, Rachael J., and Warren, William D. (2009) Phenotypic analysis of deflated/Ints7 function in Drosophila development. Developmental Dynamics, 238 (5). pp. 1131-1139. ISSN 1097-0177

The Aquaculture Genetics Group

Guy, Jeffrey A., Jerry, Dean R., and Rowland, Stuart J. (2009) Heterosis in fingerlings from a diallel cross between two wild strains of silver perch (Bidyanus bidyanus). Aquaculture Research, 40 (11). pp. 1291-1300. ISSN 1365-2109

Smith-Keune, Carolyn, and Jerry, Dean R. (2009) High levels of intra-specific variation in the NG repeat region of the Pinctada maxima N66 organic matrix protein. Aquaculture Research, 40 (9). pp. 1054-1063. ISSN 1365-2109

Fauvelot, C., Smith-Keune, C., Jerry, D.R., Buston, P.M., and Planes, S. (2009) Isolation and characterization of 16 microsatellite loci in the humbug damselfish, Dascyllus aruanus (family Pomacentridae). Molecular Ecology Resources, 9 (2). pp. 651-653. ISSN 1755-0998

Lind, Curtis E., Evans, Brad S., Knauer, Jens, Taylor, Joseph J.U., and Jerry, Dean R. (2009) Decreased genetic diversity and a reduced effective population size in cultured silver-lipped pearl oysters (Pinctada maxima). Aquaculture, 286 (1-2). pp. 12-19. ISSN 1873-5622

Edmunds, Richard C., van Herwerden, Lynne, Smith-Keune, Carolyn, and Jerry, Dean R. (2009) Comparative characterization of a temperature responsive gene (lactate dehydrogenase-B, ldh-b) in two congeneric tropical fish, Lates calcarifer and Lates niloticus. International Journal of Biological Sciences, 5 (6). pp. 558-569. ISSN 1449-2288

The Symbiosis Genomics Group

Voolstra, Christian R., Sunagawa, Shinichi, Schwarz, Jodi A., Coffroth, Mary Alice, Yellowlees, Dave, Leggat, William, and Medina, Monica (2009) Evolutionary analysis of orthologous cDNA sequences from cultured and symbiotic dinoflagellate symbionts of reef-building corals (Dinophyceae: Symbiodinium). Comparative Biochemistry and Physiology Part D: Genomics and Proteomics, 4 (2). pp. 67-74. ISSN 1744-117X

Reef, Ruth, Dunn, Simon, Levy, Oren, Dove, Sophie, Shemesh, Eli, Brickner, Itzchak, Leggat, William, and Hoegh-Guldberg, Ove (2009) Photoreactivation is the main repair pathway for UV-induced DNA damage in coral planulae. Journal of Experimental Biology, 212 . pp. 2760-2766. ISSN 1477-9145

Parasite and Pest Genetics

You, Hong, Zhang, Wenbao, Jones, Malcolm K., Gobert, Geoffrey N., Mulvenna, Jason, Rees, Glynn, Spanevello, Mark, Blair, David, Duke, Mary, Brehm, Klaus, and McManus, Donald P. (2010) Cloning and characterisation of Schistosoma japonicum insulin receptors. PLoS ONE, 5 (3). pp. 1-13. ISSN 1932-6203

Okamoto, Munehiro, Nakao, Minoru, Blair, David, Anantaphruti, Malinee T., Waikagul, Jitra, and Ito, Akira (2010) Evidence of hybridization between Taenia saginata and Taenia asiatica. Parasitology International, 59 (1). pp. 70-74. ISSN 1873-0329

Luly, J.G., Blair, David, Parsons, Jennifer G., Fox, Samantha, and VanDerWal, Jeremy (2010) Last Glacial Maximum habitat change and its effects on the grey-headed flying fox (Pteropus poliocephalus Temminck 1825). In: Altered Ecologies: fire, climate and human influence on terrestrial landscapes. Terra Australis, 32 . ANU E Press, Canberra, ACT, Australia, pp. 83-100. ISBN 978-1-921666-80-3

Narain, Kanwar, Agatsuma, Takeshi, and Blair, David (2010) Paragonimus. In: Molecular Detection of Foodborne Pathogens. CRC Press, Boca Raton, USA, pp. 827-837. ISBN 978-1-4200-7643-1

Flint, Mark, Patterson-Kane, Janet C., Limpus, Colin J., Work, Thierry M., Blair, David, and Mills, Paul C. (2009) Postmortem diagnostic investigation of disease in free-ranging marine turtle populations: a review of common pathologic findings and protocols. Journal of Veterinary Diagnostic Investigation, 21 (6). pp. 733-759. ISSN 1943-4936

Van Van, Kim, Dalsgaard, Anders, Blair, David, and Hoa Le, Thanh (2009) Haplorchis pumilio and H. taichui in Vietnam discriminated using ITS-2 DNA sequence data from adults and larvae. Experimental Parasitology, 123 (2). pp. 146-151. ISSN 1090-2449

Zhou, Yan, (2009) The Schistosoma japonicum genome reveals features of host–parasite interplay. Nature, 460 . pp. 345-352. ISSN 1476-4687

Parsons, Jennifer G., Blair, David, Luly, Jon, and Robson, Simon K.A. (2009) Bat strikes in the Australian aviation industry. Journal of Wildlife Management, 73 (4). pp. 526-529. ISSN 1937-2817

Nkouawa, Agathe, Okamoto, Munehiro, Mabou, Alida Kouojip, Edinga, Eulodie, Yamasaki, Hiroshi, Sako, Yasuhito, Nakao, Minoru, Nakaya, Kazuhiro, Blair, David, Agatsuma, Takeshi, Enyong, Peter, Shibahara, Toshiyuki, Moyou-Somo, Roger, and Ito, Akira (2009) Paragonimiasis in Cameroon: molecular identification, serodiagnosis and clinical manifestations. Transactions of the Royal Society of Tropical Medicine and Hygiene, 103 (3). pp. 255-261. ISSN 0035-9203

Barton, D.P., and Blair, D. (2009) Parasitology in northern Queensland. In: A History of Parasitology in Australia and Papua New Guinea. Raw Publishing, Blackburn, VIC, Australia, pp. 35-47. ISBN 978-0-9806338-0-1

Kolomyjec, Stephen H., Chong, Josephine Y.T., Blair, David, Gongora, Jaime, Grant, Tom R., Johnson, Christopher N., and Moran, Chris (2009) Population genetics of the platypus (Ornithorhynchus anatinus): a fine-scale look at adjacent river systems. Australian Journal of Zoology, 57 (3 & 4). pp. 225-234. ISSN 1446-5698

The Conservation and Ecological Genetics Group

Bell, Johann, Batty, Mike, Ganachaud, Alex, Gehrke, Peter, Hobday, Alistair, Hoegh-Guldberg, Ove, Johnson, Johanna, Le Borgne, Robert, Lehodey, Patrick, Lough, Janice, Pickering, Tim, Pratchett, Morgan, Sheaves, Marcus, and Waycott, Michelle (2010) Preliminary assessment of the effects of climate change on fisheries and aquaculture in the Pacific. In: Fisheries in the Economies of the Pacific Island Countries and Territories. Pacific Studies Series. Asian Development Bank, Manila, Philippines, pp. 451-469. ISBN 978-971-561-708-6

Waycott, Michelle, Duarte, Carlos M., Carruthers, Tim J.B., Orth, Robert J., Dennison, William C., Olyarnik, Suzanne, Calladine, Ainsley, Fourqurean, James W., Heck Jr., Kenneth L., Hughes, A. Randall, Kendrick, Gary A., Kenworthy, W. Judson, Short, Frederick T, and Williams, Susan L. (2009) Accelerating loss of seagrasses across the globe threatens coastal ecosystems. Proceedings of the National Academy of Sciences, 106 (30). pp. 12377-12381. ISSN 1091-6490

Boyle, M.C., FitzSimmons, N.N., Limpus, C.J., Kelez, S., Velez-Zuazo, X., and Waycott, M. (2009) Evidence for transoceanic migrations by loggerhead sea turtles in the southern Pacific Ocean. Proceedings of the Royal Society of London Series B, Biological Sciences, 276 (1664). pp. 1993-1999. ISSN 1471-2954

Hughes, A. Randall, Williams, Susan L., Duarte, Carlos M., Heck Jr, Kenneth L., and Waycott, Michelle (2009) Associations of concern: declining seagrasses and threatened dependent species. Frontiers in Ecology and the Environment, 7 (5). pp. 242-246. ISSN 1540-9309

Collier, Catherine, and Waycott, Michelle (2009) Drivers of Change to Seagrass Distributions and Communities on the Great Barrier Reef: literature review and gaps analysis.  Reef and Rainforest Research Centre, Cairns, QLD, Australia.

Algal Biology Group

Heimann, Kirsten, and Katsaros, Christos (2009) Algal cell biology and genomics. Botanica Marina, 52 . pp. 93-94. ISSN 1437-4323

Heimann, Kirsten, Klerks, Paul L., and Hasenstein, Karl H. (2009) Involvement of actin and microtubules in regulation of bioluminescence and translocation of chloroplasts in the dinoflagellate Pyrocystis lunula. Botanica Marina, 52 (2). pp. 170-177. ISSN 1437-4323


Medical Genomics Research Group, Autoimmunity Research Group, Comparative Genomics Centre,  Key words: Autoimmune diabetes, gene, genome, allele, locus, inherited, disease, Type 1 diabetes mellitus, childhood diabetes, lupus, systemic lupus erythematosus, hemolytic anaemia, hemolytic anemia, Coombs' test, antinuclear antibodies, renal failure, glomerulonephritis, gastritis, type A gastritis, pernicious anemia, immunology, popular science, biology.